The INTEC Science

To obtain fundamental knowledge of ectopic calcification

mechanisms and translate science to the clinic

EC Data & Analytics Platform

The Ectopic Calcification Data and Analytics Platform (EC-DAP) entails clinical databases and survey tools concerning patients with ectopic mineralization diseases. EC-DAP has a section for clinicians and a section for patients.



  • Nollet L, Vanakker OM. Mitochondrial dysfunction and oxidative stress in hereditary ectopic calcification diseases. Int. J. Mol. Sci. 2022; 23 (23): 15288.
  • Szeri F, Miko A, Navasiolava N, Kaposi A, Verschuere S, Molnar B, Li Q, Terry SF, Boraldi F, Uitto J, van de Wetering K, Martin L, Quaglino D, Vanakker OM, Tory K, Aranyi T. The pathogenic c.1171A>G (p.Arg391Gly) and c.2359G>A (p.Val787Ile) ABCC6 variants display incomplete penetrance causing pseudoxanthoma elasticum in a subset of individuals. Hum. Mutat. 2022 In Press
  • Nollet L, Van Gils M, Fischer S, Campens L, Karthik S, Pasch A, De Zaeytijd J, Leroy BP, Devos D, De Backer T, Coucke PJ, Vanakker OM. Serum Calcification Propensity T50 Associates with Disease Severity in Patients with Pseudoxanthoma Elasticum. J. Clin. Med. 2022;11(13):3727.